Self-sacrifice in radical S-adenosylmethionine proteins
نویسندگان
چکیده
منابع مشابه
Radical S-Adenosylmethionine Enzymes
ing a H-atom from substrate. These and other kinetics studies demonstrated that PFL-AE could undergo multiple turnover events, with the 150 PFL activations per PFL-AE reported in Table 1 not the upper limit, but rather a number limited by the PFL:PFL-AE ratio in the steady-state kinetics assays. As can be seen from the data summarized in Table 1, PFL-AE is one of the few radical SAM enzymes dem...
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S-Adenosylmethionine decarboxylase is a key enzyme for the synthesis of polyamines in mammals, plants and many other species that use aminopropyltransferases for this pathway. It catalyses the formation of S-adenosyl-1(methyl th io)-3-propylamine (decarboxyla ted S-adenosylmethionine), which is used as the aminopropyl donor. This is the sole function of decarboxylated S-adenosylmethionine. Its ...
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ژورنال
عنوان ژورنال: Current Opinion in Chemical Biology
سال: 2007
ISSN: 1367-5931
DOI: 10.1016/j.cbpa.2007.08.028